Postural function in idiopathic normal pressure hydrocephalus before and after shunt surgery: a controlled study using computerized dynamic posturography (EquiTest).
Identifieur interne : 000A45 ( Main/Exploration ); précédent : 000A44; suivant : 000A46Postural function in idiopathic normal pressure hydrocephalus before and after shunt surgery: a controlled study using computerized dynamic posturography (EquiTest).
Auteurs : F. Lundin [Suède] ; T. Ledin ; C. Wikkels ; G. LeijonSource :
- Clinical neurology and neurosurgery [ 1872-6968 ] ; 2013.
Descripteurs français
- KwdFr :
- Accident vasculaire cérébral lacunaire (anatomopathologie), Adulte d'âge moyen (MeSH), Algorithmes (MeSH), Cognition (physiologie), Dérivations du liquide céphalorachidien (MeSH), Femelle (MeSH), Humains (MeSH), Hydrocéphalie chronique de l'adulte (), Hydrocéphalie chronique de l'adulte (physiopathologie), Interprétation statistique de données (MeSH), Mâle (MeSH), Phénomènes biomécaniques (MeSH), Posture (physiologie), Sensation (physiologie), Sujet âgé (MeSH), Sujet âgé de 80 ans ou plus (MeSH), Troubles neurologiques de la marche (étiologie), Équilibre postural (physiologie).
- MESH :
- anatomopathologie : Accident vasculaire cérébral lacunaire.
- physiologie : Cognition, Posture, Sensation, Équilibre postural.
- physiopathologie : Hydrocéphalie chronique de l'adulte.
- étiologie : Troubles neurologiques de la marche.
- Adulte d'âge moyen, Algorithmes, Dérivations du liquide céphalorachidien, Femelle, Humains, Hydrocéphalie chronique de l'adulte, Interprétation statistique de données, Mâle, Phénomènes biomécaniques, Sujet âgé, Sujet âgé de 80 ans ou plus.
English descriptors
- KwdEn :
- Aged (MeSH), Aged, 80 and over (MeSH), Algorithms (MeSH), Biomechanical Phenomena (MeSH), Cerebrospinal Fluid Shunts (MeSH), Cognition (physiology), Data Interpretation, Statistical (MeSH), Female (MeSH), Gait Disorders, Neurologic (etiology), Humans (MeSH), Hydrocephalus, Normal Pressure (cerebrospinal fluid), Hydrocephalus, Normal Pressure (physiopathology), Male (MeSH), Middle Aged (MeSH), Postural Balance (physiology), Posture (physiology), Sensation (physiology), Stroke, Lacunar (pathology).
- MESH :
- cerebrospinal fluid : Hydrocephalus, Normal Pressure.
- etiology : Gait Disorders, Neurologic.
- pathology : Stroke, Lacunar.
- physiology : Cognition, Postural Balance, Posture, Sensation.
- physiopathology : Hydrocephalus, Normal Pressure.
- Aged, Aged, 80 and over, Algorithms, Biomechanical Phenomena, Cerebrospinal Fluid Shunts, Data Interpretation, Statistical, Female, Humans, Male, Middle Aged.
Abstract
INTRODUCTION
Postural dysfunction is one of the major features of idiopathic normal pressure hydrocephalus (iNPH). With computerized dynamic posturography (CDP) balance can be assessed objectively. The primary aim of this study was to describe the postural function in iNPH patients pre- and post-operatively in comparison with healthy individuals (HI) using CDP.
SUBJECTS AND METHODS
Thirty-five patients (16 M, 19 F) with a mean age of 73 (range 49-81) with iNPH, and sixteen HI (7 M, 9 F) aged 73 (62-89) were included. iNPH patients were operated on with a ventriculo-peritoneal shunt. Patients and HI were tested regarding motor function, balance and cognition. CDP, EquiTest (NeuroCom International, Clackamas, OR), was performed before and three months after shunt surgery and twice in HI, with a three-month interval.
RESULTS
Pre-operatively, the 35 patients had poorer balance measured with the Sensory Organizing Test (SOT) score in every condition (p=0.01 in SOT 1 and p<0.001 in SOT 2-6) compared to the HI. The greatest difference was in test conditions measuring mainly vestibular function, where loss of balance (LOB) was frequent. Twenty patients were evaluated three months after shunt surgery and 18/20 (90%) of them were considered shunt responders, with a mean improvement of motor score of 26% (range 5-67%). There was an improvement post-operatively in the weighted composite SOT score (p<0.05) but no significant change in any of the SOT conditions. LOB was not significantly reduced in any of the test conditions.
CONCLUSION
CDP showed that the patients had a poorer balance than the HI. The greatest difference was in SOT 5-6, indicating that the postural disturbance is of primarily central vestibular origin. There was a slight improvement of balance post-operatively.
DOI: 10.1016/j.clineuro.2013.02.015
PubMed: 23489444
Affiliations:
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Leijon</name></author></titleStmt><publicationStmt><idno type="wicri:source">PubMed</idno><date when="2013">2013</date><idno type="RBID">pubmed:23489444</idno><idno type="pmid">23489444</idno><idno type="doi">10.1016/j.clineuro.2013.02.015</idno><idno type="wicri:Area/Main/Corpus">000A58</idno><idno type="wicri:explorRef" wicri:stream="Main" wicri:step="Corpus" wicri:corpus="PubMed">000A58</idno><idno type="wicri:Area/Main/Curation">000A58</idno><idno type="wicri:explorRef" wicri:stream="Main" wicri:step="Curation">000A58</idno><idno type="wicri:Area/Main/Exploration">000A58</idno></publicationStmt><sourceDesc><biblStruct><analytic><title xml:lang="en">Postural function in idiopathic normal pressure hydrocephalus before and after shunt surgery: a controlled study using computerized dynamic posturography (EquiTest).</title><author><name sortKey="Lundin, F" sort="Lundin, F" uniqKey="Lundin F" first="F" last="Lundin">F. Lundin</name><affiliation wicri:level="1"><nlm:affiliation>Department of Clinical and Experimental Medicine, Faculty of Health Sciences, Linköping University, Sweden. Fredrik.Lundin@lio.se</nlm:affiliation><country xml:lang="fr">Suède</country><wicri:regionArea>Department of Clinical and Experimental Medicine, Faculty of Health Sciences, Linköping University</wicri:regionArea><wicri:noRegion>Linköping University</wicri:noRegion></affiliation></author><author><name sortKey="Ledin, T" sort="Ledin, T" uniqKey="Ledin T" first="T" last="Ledin">T. Ledin</name></author><author><name sortKey="Wikkels, C" sort="Wikkels, C" uniqKey="Wikkels C" first="C" last="Wikkels">C. Wikkels</name></author><author><name sortKey="Leijon, G" sort="Leijon, G" uniqKey="Leijon G" first="G" last="Leijon">G. Leijon</name></author></analytic><series><title level="j">Clinical neurology and neurosurgery</title><idno type="eISSN">1872-6968</idno><imprint><date when="2013" type="published">2013</date></imprint></series></biblStruct></sourceDesc></fileDesc><profileDesc><textClass><keywords scheme="KwdEn" xml:lang="en"><term>Aged (MeSH)</term><term>Aged, 80 and over (MeSH)</term><term>Algorithms (MeSH)</term><term>Biomechanical Phenomena (MeSH)</term><term>Cerebrospinal Fluid Shunts (MeSH)</term><term>Cognition (physiology)</term><term>Data Interpretation, Statistical (MeSH)</term><term>Female (MeSH)</term><term>Gait Disorders, Neurologic (etiology)</term><term>Humans (MeSH)</term><term>Hydrocephalus, Normal Pressure (cerebrospinal fluid)</term><term>Hydrocephalus, Normal Pressure (physiopathology)</term><term>Male (MeSH)</term><term>Middle Aged (MeSH)</term><term>Postural Balance (physiology)</term><term>Posture (physiology)</term><term>Sensation (physiology)</term><term>Stroke, Lacunar (pathology)</term></keywords><keywords scheme="KwdFr" xml:lang="fr"><term>Accident vasculaire cérébral lacunaire (anatomopathologie)</term><term>Adulte d'âge moyen (MeSH)</term><term>Algorithmes (MeSH)</term><term>Cognition (physiologie)</term><term>Dérivations du liquide céphalorachidien (MeSH)</term><term>Femelle (MeSH)</term><term>Humains (MeSH)</term><term>Hydrocéphalie chronique de l'adulte ()</term><term>Hydrocéphalie chronique de l'adulte (physiopathologie)</term><term>Interprétation statistique de données (MeSH)</term><term>Mâle (MeSH)</term><term>Phénomènes biomécaniques (MeSH)</term><term>Posture (physiologie)</term><term>Sensation (physiologie)</term><term>Sujet âgé (MeSH)</term><term>Sujet âgé de 80 ans ou plus (MeSH)</term><term>Troubles neurologiques de la marche (étiologie)</term><term>Équilibre postural (physiologie)</term></keywords><keywords scheme="MESH" qualifier="anatomopathologie" xml:lang="fr"><term>Accident vasculaire cérébral lacunaire</term></keywords><keywords scheme="MESH" qualifier="cerebrospinal fluid" xml:lang="en"><term>Hydrocephalus, Normal Pressure</term></keywords><keywords scheme="MESH" qualifier="etiology" xml:lang="en"><term>Gait Disorders, Neurologic</term></keywords><keywords scheme="MESH" qualifier="pathology" xml:lang="en"><term>Stroke, Lacunar</term></keywords><keywords scheme="MESH" qualifier="physiologie" xml:lang="fr"><term>Cognition</term><term>Posture</term><term>Sensation</term><term>Équilibre postural</term></keywords><keywords scheme="MESH" qualifier="physiology" xml:lang="en"><term>Cognition</term><term>Postural Balance</term><term>Posture</term><term>Sensation</term></keywords><keywords scheme="MESH" qualifier="physiopathologie" xml:lang="fr"><term>Hydrocéphalie chronique de l'adulte</term></keywords><keywords scheme="MESH" qualifier="physiopathology" xml:lang="en"><term>Hydrocephalus, Normal Pressure</term></keywords><keywords scheme="MESH" qualifier="étiologie" xml:lang="fr"><term>Troubles neurologiques de la marche</term></keywords><keywords scheme="MESH" xml:lang="en"><term>Aged</term><term>Aged, 80 and over</term><term>Algorithms</term><term>Biomechanical Phenomena</term><term>Cerebrospinal Fluid Shunts</term><term>Data Interpretation, Statistical</term><term>Female</term><term>Humans</term><term>Male</term><term>Middle Aged</term></keywords><keywords scheme="MESH" xml:lang="fr"><term>Adulte d'âge moyen</term><term>Algorithmes</term><term>Dérivations du liquide céphalorachidien</term><term>Femelle</term><term>Humains</term><term>Hydrocéphalie chronique de l'adulte</term><term>Interprétation statistique de données</term><term>Mâle</term><term>Phénomènes biomécaniques</term><term>Sujet âgé</term><term>Sujet âgé de 80 ans ou plus</term></keywords></textClass></profileDesc></teiHeader><front><div type="abstract" xml:lang="en"><p><b>INTRODUCTION</b></p><p>Postural dysfunction is one of the major features of idiopathic normal pressure hydrocephalus (iNPH). With computerized dynamic posturography (CDP) balance can be assessed objectively. The primary aim of this study was to describe the postural function in iNPH patients pre- and post-operatively in comparison with healthy individuals (HI) using CDP.</p></div><div type="abstract" xml:lang="en"><p><b>SUBJECTS AND METHODS</b></p><p>Thirty-five patients (16 M, 19 F) with a mean age of 73 (range 49-81) with iNPH, and sixteen HI (7 M, 9 F) aged 73 (62-89) were included. iNPH patients were operated on with a ventriculo-peritoneal shunt. Patients and HI were tested regarding motor function, balance and cognition. CDP, EquiTest (NeuroCom International, Clackamas, OR), was performed before and three months after shunt surgery and twice in HI, with a three-month interval.</p></div><div type="abstract" xml:lang="en"><p><b>RESULTS</b></p><p>Pre-operatively, the 35 patients had poorer balance measured with the Sensory Organizing Test (SOT) score in every condition (p=0.01 in SOT 1 and p<0.001 in SOT 2-6) compared to the HI. The greatest difference was in test conditions measuring mainly vestibular function, where loss of balance (LOB) was frequent. Twenty patients were evaluated three months after shunt surgery and 18/20 (90%) of them were considered shunt responders, with a mean improvement of motor score of 26% (range 5-67%). There was an improvement post-operatively in the weighted composite SOT score (p<0.05) but no significant change in any of the SOT conditions. LOB was not significantly reduced in any of the test conditions.</p></div><div type="abstract" xml:lang="en"><p><b>CONCLUSION</b></p><p>CDP showed that the patients had a poorer balance than the HI. The greatest difference was in SOT 5-6, indicating that the postural disturbance is of primarily central vestibular origin. There was a slight improvement of balance post-operatively.</p></div></front></TEI><pubmed><MedlineCitation Status="MEDLINE" Owner="NLM"><PMID Version="1">23489444</PMID><DateCompleted><Year>2014</Year><Month>04</Month><Day>02</Day></DateCompleted><DateRevised><Year>2013</Year><Month>09</Month><Day>02</Day></DateRevised><Article PubModel="Print-Electronic"><Journal><ISSN IssnType="Electronic">1872-6968</ISSN><JournalIssue CitedMedium="Internet"><Volume>115</Volume><Issue>9</Issue><PubDate><Year>2013</Year><Month>Sep</Month></PubDate></JournalIssue><Title>Clinical neurology and neurosurgery</Title><ISOAbbreviation>Clin Neurol Neurosurg</ISOAbbreviation></Journal><ArticleTitle>Postural function in idiopathic normal pressure hydrocephalus before and after shunt surgery: a controlled study using computerized dynamic posturography (EquiTest).</ArticleTitle><Pagination><MedlinePgn>1626-31</MedlinePgn></Pagination><ELocationID EIdType="doi" ValidYN="Y">10.1016/j.clineuro.2013.02.015</ELocationID><ELocationID EIdType="pii" ValidYN="Y">S0303-8467(13)00068-1</ELocationID><Abstract><AbstractText Label="INTRODUCTION" NlmCategory="BACKGROUND">Postural dysfunction is one of the major features of idiopathic normal pressure hydrocephalus (iNPH). With computerized dynamic posturography (CDP) balance can be assessed objectively. The primary aim of this study was to describe the postural function in iNPH patients pre- and post-operatively in comparison with healthy individuals (HI) using CDP.</AbstractText><AbstractText Label="SUBJECTS AND METHODS" NlmCategory="METHODS">Thirty-five patients (16 M, 19 F) with a mean age of 73 (range 49-81) with iNPH, and sixteen HI (7 M, 9 F) aged 73 (62-89) were included. iNPH patients were operated on with a ventriculo-peritoneal shunt. Patients and HI were tested regarding motor function, balance and cognition. CDP, EquiTest (NeuroCom International, Clackamas, OR), was performed before and three months after shunt surgery and twice in HI, with a three-month interval.</AbstractText><AbstractText Label="RESULTS" NlmCategory="RESULTS">Pre-operatively, the 35 patients had poorer balance measured with the Sensory Organizing Test (SOT) score in every condition (p=0.01 in SOT 1 and p<0.001 in SOT 2-6) compared to the HI. The greatest difference was in test conditions measuring mainly vestibular function, where loss of balance (LOB) was frequent. Twenty patients were evaluated three months after shunt surgery and 18/20 (90%) of them were considered shunt responders, with a mean improvement of motor score of 26% (range 5-67%). There was an improvement post-operatively in the weighted composite SOT score (p<0.05) but no significant change in any of the SOT conditions. LOB was not significantly reduced in any of the test conditions.</AbstractText><AbstractText Label="CONCLUSION" NlmCategory="CONCLUSIONS">CDP showed that the patients had a poorer balance than the HI. The greatest difference was in SOT 5-6, indicating that the postural disturbance is of primarily central vestibular origin. There was a slight improvement of balance post-operatively.</AbstractText><CopyrightInformation>Copyright © 2013 Elsevier B.V. All rights reserved.</CopyrightInformation></Abstract><AuthorList CompleteYN="Y"><Author ValidYN="Y"><LastName>Lundin</LastName><ForeName>F</ForeName><Initials>F</Initials><AffiliationInfo><Affiliation>Department of Clinical and Experimental Medicine, Faculty of Health Sciences, Linköping University, Sweden. Fredrik.Lundin@lio.se</Affiliation></AffiliationInfo></Author><Author ValidYN="Y"><LastName>Ledin</LastName><ForeName>T</ForeName><Initials>T</Initials></Author><Author ValidYN="Y"><LastName>Wikkelsø</LastName><ForeName>C</ForeName><Initials>C</Initials></Author><Author ValidYN="Y"><LastName>Leijon</LastName><ForeName>G</ForeName><Initials>G</Initials></Author></AuthorList><Language>eng</Language><PublicationTypeList><PublicationType UI="D016428">Journal Article</PublicationType></PublicationTypeList><ArticleDate DateType="Electronic"><Year>2013</Year><Month>03</Month><Day>11</Day></ArticleDate></Article><MedlineJournalInfo><Country>Netherlands</Country><MedlineTA>Clin Neurol Neurosurg</MedlineTA><NlmUniqueID>7502039</NlmUniqueID><ISSNLinking>0303-8467</ISSNLinking></MedlineJournalInfo><CitationSubset>IM</CitationSubset><MeshHeadingList><MeshHeading><DescriptorName UI="D000368" MajorTopicYN="N">Aged</DescriptorName></MeshHeading><MeshHeading><DescriptorName UI="D000369" MajorTopicYN="N">Aged, 80 and over</DescriptorName></MeshHeading><MeshHeading><DescriptorName UI="D000465" MajorTopicYN="N">Algorithms</DescriptorName></MeshHeading><MeshHeading><DescriptorName UI="D001696" MajorTopicYN="N">Biomechanical Phenomena</DescriptorName></MeshHeading><MeshHeading><DescriptorName UI="D002557" MajorTopicYN="Y">Cerebrospinal Fluid Shunts</DescriptorName></MeshHeading><MeshHeading><DescriptorName UI="D003071" MajorTopicYN="N">Cognition</DescriptorName><QualifierName UI="Q000502" MajorTopicYN="N">physiology</QualifierName></MeshHeading><MeshHeading><DescriptorName UI="D003627" MajorTopicYN="N">Data Interpretation, Statistical</DescriptorName></MeshHeading><MeshHeading><DescriptorName UI="D005260" MajorTopicYN="N">Female</DescriptorName></MeshHeading><MeshHeading><DescriptorName UI="D020233" MajorTopicYN="N">Gait Disorders, Neurologic</DescriptorName><QualifierName UI="Q000209" MajorTopicYN="N">etiology</QualifierName></MeshHeading><MeshHeading><DescriptorName UI="D006801" MajorTopicYN="N">Humans</DescriptorName></MeshHeading><MeshHeading><DescriptorName UI="D006850" MajorTopicYN="N">Hydrocephalus, Normal Pressure</DescriptorName><QualifierName UI="Q000134" MajorTopicYN="N">cerebrospinal fluid</QualifierName><QualifierName UI="Q000503" MajorTopicYN="Y">physiopathology</QualifierName></MeshHeading><MeshHeading><DescriptorName UI="D008297" MajorTopicYN="N">Male</DescriptorName></MeshHeading><MeshHeading><DescriptorName UI="D008875" MajorTopicYN="N">Middle Aged</DescriptorName></MeshHeading><MeshHeading><DescriptorName UI="D004856" MajorTopicYN="N">Postural Balance</DescriptorName><QualifierName UI="Q000502" MajorTopicYN="Y">physiology</QualifierName></MeshHeading><MeshHeading><DescriptorName UI="D011187" MajorTopicYN="N">Posture</DescriptorName><QualifierName UI="Q000502" MajorTopicYN="N">physiology</QualifierName></MeshHeading><MeshHeading><DescriptorName UI="D012677" MajorTopicYN="N">Sensation</DescriptorName><QualifierName UI="Q000502" MajorTopicYN="N">physiology</QualifierName></MeshHeading><MeshHeading><DescriptorName UI="D059409" MajorTopicYN="N">Stroke, Lacunar</DescriptorName><QualifierName UI="Q000473" MajorTopicYN="N">pathology</QualifierName></MeshHeading></MeshHeadingList><KeywordList Owner="NOTNLM"><Keyword MajorTopicYN="N">Computerized dynamic posturography</Keyword><Keyword MajorTopicYN="N">Idiopathic normal pressure hydrocephalus</Keyword><Keyword MajorTopicYN="N">Postural function</Keyword><Keyword MajorTopicYN="N">Shunt surgery</Keyword></KeywordList></MedlineCitation><PubmedData><History><PubMedPubDate PubStatus="received"><Year>2012</Year><Month>08</Month><Day>25</Day></PubMedPubDate><PubMedPubDate PubStatus="revised"><Year>2013</Year><Month>01</Month><Day>10</Day></PubMedPubDate><PubMedPubDate PubStatus="accepted"><Year>2013</Year><Month>02</Month><Day>11</Day></PubMedPubDate><PubMedPubDate PubStatus="entrez"><Year>2013</Year><Month>3</Month><Day>16</Day><Hour>6</Hour><Minute>0</Minute></PubMedPubDate><PubMedPubDate PubStatus="pubmed"><Year>2013</Year><Month>3</Month><Day>16</Day><Hour>6</Hour><Minute>0</Minute></PubMedPubDate><PubMedPubDate PubStatus="medline"><Year>2014</Year><Month>4</Month><Day>3</Day><Hour>6</Hour><Minute>0</Minute></PubMedPubDate></History><PublicationStatus>ppublish</PublicationStatus><ArticleIdList><ArticleId IdType="pubmed">23489444</ArticleId><ArticleId IdType="pii">S0303-8467(13)00068-1</ArticleId><ArticleId IdType="doi">10.1016/j.clineuro.2013.02.015</ArticleId></ArticleIdList></PubmedData></pubmed><affiliations><list><country><li>Suède</li></country></list><tree><noCountry><name sortKey="Ledin, T" sort="Ledin, T" uniqKey="Ledin T" first="T" last="Ledin">T. Ledin</name><name sortKey="Leijon, G" sort="Leijon, G" uniqKey="Leijon G" first="G" last="Leijon">G. Leijon</name><name sortKey="Wikkels, C" sort="Wikkels, C" uniqKey="Wikkels C" first="C" last="Wikkels">C. Wikkels</name></noCountry><country name="Suède"><noRegion><name sortKey="Lundin, F" sort="Lundin, F" uniqKey="Lundin F" first="F" last="Lundin">F. Lundin</name></noRegion></country></tree></affiliations></record>Pour manipuler ce document sous Unix (Dilib)
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